Top HealthTech Startups in Germany

What are HealthTech Startups?

Healthtech startups are innovative companies operating at the intersection of healthcare and technology, leveraging advanced technological solutions to address and enhance various aspects of the healthcare industry. These startups often develop and implement cutting-edge technologies, such as artificial intelligence, telemedicine, wearable devices, and data analytics, to improve patient care, streamline healthcare operations, and facilitate medical research.

Read also - Top 10 HealthTech Startups in Netherland

By introducing novel solutions, health-tech startups aim to optimize the delivery of healthcare services, enhance diagnostic capabilities, and promote preventive healthcare measures. Whether through digital health platforms, remote monitoring tools, or personalized health applications, these startups contribute to the ongoing digital transformation of the healthcare sector, ultimately striving to make healthcare more accessible, efficient, and patient-centred.

Read also - Top 10 HealthTech Startups in Italy

Top HealthTech Startups in Germany

Orbem

Founded in 2019 in Munich, Germany, by Pedro Gomez, Orbem is a trailblazer in health tech and AI. The startup has gained recognition for its AI-powered MRI platform designed for scanning biological samples. The mission at Orbem is to advance medical imaging technologies, particularly in MRI, using artificial intelligence.

Read also - Top 10 HealthTech Startups in Malta

In its Series A funding round, Orbem successfully raised $32 million, with investors such as 83North, TVC, and Possible Ventures expressing confidence in its innovative approach. Operating on a B2B and SAAS model, Orbem contributes significantly to the evolution of diagnostic capabilities.

Sport Alliance

Based in Hamburg, Germany, Sport Alliance was founded in 2011 by Daniel Hanelt with a vision to create software solutions for gyms and fitness providers. The startup's mission is to empower fitness businesses through advanced software tools.

Read also - Top 10 HealthTech Startups in Poland

Sport Alliance has become a significant player in the health tech and sportstech sectors. In its Series D funding round, the startup secured an impressive $100 million, with PSG Equity among the key investors. Operating on a B2B and SAAS model, Sport Alliance continues to shape the landscape of fitness technology.

AMSilk

Founded in 2008 in Munich, Germany, AMSilk is a biofabrication and biotech startup that specializes in developing bio-fabricated silk protein materials. AMSilk's mission is rooted in leveraging nature's building blocks to create sustainable and advanced materials.

Read also - Top 10 HealthTech Startups in Slovakia

With a focus on B2B interactions, the startup has successfully raised $27 million in its Series C funding round, with Novo A/S as a notable investor. AMSilk's contributions span the intersection of health tech, biotech, and manufacturing.

Modag

MODAG is a German biotech company developing new therapies and diagnostic tools for neurodegenerative diseases like Parkinson’s and Multiple System Atrophy (MSA). Its main drug, Emrusolmin (anle138b), targets harmful protein clumps in the brain to slow disease progression.
The company combines its patented compounds with advanced diagnostics for early detection and disease-modifying treatments.

MODAG works closely with leading research institutions and patient organizations to advance its pipeline. Headquartered in Hochtechnologiepark Wendelsheim, Germany, with R&D facilities in Munich and Göttingen, MODAG focuses on turning innovative research into clinical applications. Collaborations with top US and European research centers, along with the expertise of its management team, help accelerate development of treatments for severe neurological disorders.

Floy

Founded in 2021 in Munich by Benedikt Schneider, Floy has made strides in the intersection of health tech and biotech with its AI platform for radiology diagnostics. The founders aimed to enhance diagnostic capabilities through artificial intelligence.

Read also - Top 10 Health-Tech Startups in Norway

Floy successfully secured $5.8 million in seed funding, with investments from xdeck and 10x Founders. Operating on a B2B model, Floy is contributing to the advancement of AI-driven solutions in the field of medical diagnostics.

Heidelberg Pharma

Heidelberg Pharma AG is a German biopharmaceutical company developing targeted cancer treatments using its proprietary Antibody-Drug Conjugate (ADC) technology, called the ATAC platform. The company’s approach combines antibodies with a powerful toxin called Amanitin, derived from the Green Deathcap mushroom, to deliver treatment directly to cancer cells while sparing healthy tissue.

Heidelberg Pharma has a strong pipeline of drug candidates for different cancers, including a lead candidate for multiple myeloma, and also offers preclinical contract research services. Its ADC technology works by loading selected antibodies with toxic compounds, which are carried into diseased cells. Once inside, the toxins kill the cancer cells. The company’s ADC toolbox is designed to overcome tumor resistance and treat a variety of blood and solid cancers effectively.

Ottonova

Established in 2016 in Munich by Roman Rittweger, Ottonova has positioned itself as a comprehensive digital health insurance solution. The founder aimed to revolutionize health insurance services through digital means.

Read also - Top 10 HealthTech Startups in Switzerland

Ottonova secured $34 million in its Series F funding round, with participation from HV Capital, Earlybird Venture Capital, btov Partners, Vorwerk Ventures, and TEV Ventures. Operating on both B2B and B2C models, Ottonova continues to innovate in the insuretech space.

Cytena

CYTENA is founded in Germany in 2014 and now part of the BICO Group, specializes in high-precision automated instruments for handling biological cells. Its patented single-cell dispensing technology allows researchers to isolate, dispense, and image individual cells efficiently and reproducibly. The company core technology is a single-cell printer system that gently and sterily isolates and dispenses individual cells into droplets.

CYTENA instruments help accelerate drug discovery, stable cell line development, and genetic analysis by providing precise control over single cells. With automated isolation and clonality assurance, their system can select cells based on morphology and handle many common cell types, including bacteria. High viability rates make CYTENA instruments ideal for cell line development, single-cell analysis, and other downstream applications, empowering researchers to bring therapies to patients faster.

Patient21

Established in 2018 in Berlin by Dr. Daniel Nathrath, Dr. Julius Oster, and Luisa Menezes, Patient21 is a digital healthcare platform with physical clinics. The founders aimed to create a seamless healthcare experience for patients.

Read also - Top 10 HealthTech Startups in Denmark

In its Series C funding round, Patient21 secured an impressive $110 million, with Target Global and TDJ Pitango Ventures among the investors. Operating on a B2C model, Patient21 is making healthcare more accessible and convenient.

HMNC Brain Health

Based in Munich, HMNC Brain Health was founded in 2020 by Prof. Dr. med. Nikolai Axmacher, Prof. Dr. Dr. Thomas Schultz, and Dr. Martin Rossner. The founders aimed to advance precision medicine solutions for mental health.

Read also - Top 10 AI Copywriting Tools

HMNC Brain Health successfully raised $14 million, with ALSTIN Capital as a key investor. Operating on a B2B model, the startup contributes to innovative mental health solutions.

Wellster

Wellster is a healthtech startup that wants to make it easier for people to get effective treatments for everyday health problems. Wellster is a healthtech startup aimed at giving more people easy access to effective treatments for everyday health problems.

Read also - Top 10 Fintech Startups in Spain

Wellster is focused on making effective medical treatments more accessible. Despite the challenges of Germany's regulated market, this healthtech offers a solution that can grow and reach more people.

Climedo

Climedo is a trusted partner for the pharmaceutical, medical technology, research organizations, and academic sectors, with over 1.7 million patients enrolled so far. Climedo offers an all-in-one solution for collecting and managing clinical data in non-interventional studies and real-world research.

Using a patient-centered approach and real-time data, Climedo helps clients engage better with healthcare professionals and key experts. This increases awareness, encourages scientific discussions, and speeds up the launch of new medical innovations to reach more patients faster.

Cardiac Dimensions

Cardiac Dimensions is a medical device company with German operations through Cardiac Dimensions GmbH and Cardiac Dimensions Europe GmbH, based in Frankfurt. These entities support the development of the Carillon Mitral Contour System, a minimally invasive, catheter-based device designed to treat heart failure caused by mitral valve leakage.

The Carillon system reshapes the mitral valve to improve heart function without surgery. It is the only indirect, no-touch mitral valve repair therapy that helps remodel the left ventricle and supports long-term survival. Carillon therapy can also be used alongside other heart failure treatments if needed, offering patients a safer, effective, non-surgical option to live longer and healthier lives.

Dermaliq

Dermaliq Therapeutics GmbH based in Heidelberg, Germany is a clinical-stage dermatology company spun off from Novaliq GmbH in 2021. The company develops topical skin treatments using its proprietary hyliQ® technology, designed to improve drug delivery and effectiveness for skin conditions.

Dermaliq focuses on creating advanced therapies and medical skincare products for conditions like alopecia and plaque psoriasis. Its hyliQ® technology allows drugs to penetrate skin tissues more effectively while reducing side effects enabling highly effective liquid formulations with excellent cosmetic properties for millions of patients.

Caresyntax

Caresyntax Germany is the German branch of a global surgical intelligence company founded in 2013. With headquarters in Berlin and San Francisco, Caresyntax provides an AI-powered platform that helps hospitals, insurers, and medical device companies improve surgical safety and efficiency.

The platform supports the entire surgical process: it optimizes workflows before surgery, provides real-time tools during procedures, and monitors safety after surgery. It also delivers data analytics and insights to medical device companies and insurers, helping drive innovation and improve healthcare delivery worldwide.

Frequently asked questions (FAQs)

Name the Top 12 HealthTech Startups in Germany?

Orbem, Sport Alliance, AMSilk, CatalYm, Floy, Habyt, Ottonova, Tubulis, Patient21, HMNC Brain, Wellster and Climedo Health are Top 12 HealthTech Startups in Germany.

Who founded HMNC Brain Health?

HMNC Brain Health was founded in 2020 by Prof. Dr. med. Nikolai Axmacher, Prof. Dr. Dr. Thomas Schultz, and Dr. Martin Rossner